Iclusig, a kinase inhibitor, received a positive opinion for use alongside low-intensity chemotherapy in adults with newly identified disease.

BACKGROUND: Oscillatory shear stress (OSS), resulting from disturbed blood flow, is implicated in atherosclerotic plaque formation by incompletely understood mechanisms. This study aims to elucidate ...

EMA recommends Kygevvi for rare thymidine kinase 2 deficiency. It is the first authorized treatment for this disease.

Few effective treatments exist to treat neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS). 1 Existing treatments focus on ...

What Is Thymidine Kinase 2 Deficiency (TK2d)? Thymidine kinase 2 deficiency (TK2d) mainly causes muscle weakness. It’s a very rare mitochondrial disease. Mitochondria are tiny organ-like structures ...

Researchers identify beta catenin protein degradation as a therapeutic vulnerability in B cell acute lymphoblastic leukaemia, supporting the repurposing of glycogen synthase kinase 3 beta inhibitors.

Kinases are crucial to many signaling pathways, and when they don't work properly, the consequences can lead to problems, including cancer, immune diseases, and neurological disorders. But there are ...

Sino Biological, Inc. is proud to announce the launch of its innovative SwiftFluo ® TR-FRET Kinase Assay Kits, a ready-to-use ...

Researchers from the University of Seville have participated in research to identify the molecular details of the regulation ...

Designed to balance ease of use, cost efficiency, and reproducible data, which are critical requirements for successful high-throughput screening campaigns ...