Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

A decade ago, the Nobel Prize in Chemistry was awarded to a trio of researchers for the development of super-resolved fluorescence microscopy. The announcement at the time stated that the researchers’ ...

Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy. 1 In addition to scanning the lateral x ...

Open-source core technology embedded inside projector hardware enables high-speed, auto-polarization modulated 3D structured illumination microscopy (SIM) imaging. 3DSIM reconstruction of plant and ...

Researchers have developed a compact handheld imaging probe that could expand the clinical and research use of photoacoustic ...

When trying to measure molecular structures with nanometer precision, every bit of noise shows up in the data: someone walking past the microscope, tiny vibrations in the building and even the traffic ...

MINFLUX is a super-resolution microscopy protocol designed to improve the localizing of specific photon emitters in space. Developed in 2016 by a German team including super-resolution pioneer and ...

What is the Diffraction Limit? The diffraction limit is a fundamental barrier in optical microscopy that sets the minimum size of features that can be resolved using conventional light microscopes. It ...

Computational fluorescence microscopy (CFM) requires accurate point spread function (PSF) characterization for high-quality ...