Continuous countercurrent tangential chromatography (CCTC) is a column-free process that provides a scalable, disposable, and cost-saving alternative to column chromatography. As advances in ...

The authors examine the challenges of integrating a large-scale chromatography and nanofiltration process for purification of a polyclonal antibody. Biomanufacturing of a biopharmaceutical blockbuster ...

Disposability as a general biomanufacturing strategy arose from analysis of single-use economics, particularly with respect to cleaning and related validation for fixed-tank systems. Cost benefits ...

Although biopharmaceutical manufacturing covers an extensive range, it is essential that each iteration of a unit operation is in compliance with an unyielding set of operational parameters and ...