Toll-like receptor 4 (TLR4) signalling involves two branches. The early recruitment of the adaptor proteins TIRAP and MYD88 to plasma membrane-resident TLR4 promotes the expression of pro-inflammatory ...
Association of genes copy number in extracellular DNA in patients with prostate cancer and sensitivity to radiotherapy. This is an ASCO Meeting Abstract from the 2021 ASCO Annual Meeting I. This ...
The immune system uses a large number of proteins to sense the presence of microbes, including a family of proteins known as TLRs. The function of TLRs on immune cells known as DCs and macrophages has ...
Toll-like receptors (TLRs) are essential components of the immune response to fungal pathogens. We examined the role of TLR polymorphisms in conferring a risk of invasive aspergillosis among ...
This new article publication from Acta Pharmaceutica Sinica B, discusses a fully synthetic Tn-based three-component cancer vaccine using covalently linked TLR4 ligand MPLA and iNKT cell agonist ...
The worldwide spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused the global coronavirus disease 2019 (COVID-19) pandemic. To date, this pandemic has infected over 207 ...
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