For decades, dopamine has been celebrated in neuroscience as the quintessential "reward molecule"—a chemical herald of ...

Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...

A longevity-linked metabolite restored key memory processes in Alzheimer’s models, highlighting aging biology as a promising therapeutic target. Singapore ranks among the countries with the longest ...

Memory formation and maintenance fundamentally rely on intricate molecular processes that regulate synaptic strength. Central to this phenomenon is synaptic plasticity – the capacity of neural ...

New research on the hippocampus, a brain area essential for memory, suggests that new rules of synaptic plasticity best explain how brain activity continually reshapes the way memories are recorded in ...

A study mapped genes linked to schizophrenia and uncovered a mechanism that disrupts synaptic plasticity in affected individuals. The researchers showed the role of three proteins in mediating the ...

Presented at IEDM 2016, Breakthrough Suggests Path to Embedding Neuromorphic Learning in Low-power Devices that Could Enable Autonomous Systems Leti researchers have demonstrated that memristive ...

This mitochondrial process supports the brain cells essential to learning, memory and social recognition. We know that mitochondria are the powerhouses of the cell, but what role do they play in ...

A comprehensive mini-review published today after peer review in Brain Medicine by Dr. Tao Ma and colleagues at Wake Forest University School of Medicine synthesizes emerging evidence that two ...

As animals experience new things, the connections between neurons, called synapses, strengthen or weaken in response to events and the activity they cause in the brain. Neuroscientists believe that ...

A new study led by researchers at Tampere University has mapped genes linked to schizophrenia and uncovered a mechanism that disrupts synaptic plasticity in affected individuals. The researchers ...