As organisms develop from embryos, groups of cells migrate and reshape themselves to form all manner of complex tissues.

An increasing amount of research indicates that more translational and appropriate observations can be made with organoids and micro-tissues in comparison with 2D monolayer cell models. This is most ...

In research that could shed light on the growth and formation of complex tissue architectures, Brown University engineers ...

Drastic differences in the ways cells behave and respond to drugs are observed when cells are cultured using 3D instead of 2D approaches. These differences are driving the adoption of more advanced ...

Evaluating Anticancer Drugs and Building Tissue and Tumor Co-Culture Models Among Uses The need for new tools and technologies to decrease the cost of drug discovery and reduce animal testing has been ...

The utilization of multi-cell tumor spheroids as an oncology research model has quickly increased because of a greater understanding of the effects of the tumor microenvironment, along with the ...

In basic and applied biology research, such as investigations of stem cells and drug screening, spheroid cell cultures are valuable, providing a more realistic test environment than the 2D cultures ...

Spheroid Cell Culture: New Dimensions in 3D Assays from thescientistllc on Vimeo. High attrition in clinical trials and the need to replace animal models in a variety of applications has driven ...

Isolation of spheroid-forming cells is important to investigate cancer stem cell (CSC) characteristics. However, conventional tumor spheroid culture methods have not proven suitable because the ...

Researchers have used the ALMA telescope and found old elliptical galaxies in the universe can form from intense star formation within early galaxy cores. An international team of researchers ...