Sequence analysis is a cornerstone of modern bioinformatics, encompassing the computational exploration of biological sequences—be they DNA, RNA or proteins—to reveal insights into structure, function ...

What is Third-Generation Sequencing? Third-generation sequencing, also known as long-read sequencing, refers to the latest advancements in DNA sequencing technologies that enable the analysis of ...

Human disease is complex and influenced by a wide range of genomic variants. Sequencing accuracy is paramount in order to detect this vast array of genomic dysfunction. In genomic and multiomic ...

The Next Generation Sequencing (NGS) field has been in constant flux since a wave of newcomers entered the field several years ago that changed the game. The startups offered sequencing users new ...

An individual’s genome is identifiable. But datasets of RNA sequences from single cells are like a blurry photocopy of the genome. The sequence numbers are small, the data are noisy, and the sequences ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

SOX/FOLFOX+nivolumab followed by conversion surgery for HER2 negative primary gastric or gastroesophageal junction cancer with oligo-metastasis or borderline resectable tumors: Early results of a ...

The first resource containing high-resolution DNA sequencing data for over 37,000 children and parents collected over multiple decades from across the UK is now available to researchers worldwide. The ...