The proteome is an incredibly rich and dynamic source of biological information, key to understanding how cells function in sickness and health. Genes and genomes give hints as to what might happen in ...

The global Human Proteome Project released its 2023 report describing new proteins identified in the past year, as well as new work beginning to characterize the functions of these proteins. The ...

Matthias Trost (left) is a Professor at Newcastle University (UK) with a lab comprising three focuses: method development for proteomics, the application of mass spectrometry in drug discovery and the ...

Following on from his exposé of the dearth of specificity in our vocabulary surrounding the proteome and his emphasis that individual proteoforms should be the focus of our proteomic investigations, ...

A new study maps the biological influences on thousands of plasma proteins, revealing potential disease biomarkers and drug targets, providing hope for more precise, personalized treatments. Study: ...

A milestone in biology has been achieved thanks to artificial intelligence (AI) machine learning and applied physics. A new peer-reviewed study by researchers affiliated with Harvard John A. Paulson ...

Despite their sophistication and power, traditional proteomics technologies have failed to provide comprehensive coverage. For example, with conventional mass spectrometry, a single experiment ...

Development and validation of a gene expression signature based on RB1, PTEN, and TP53 in patients with metastatic hormone-sensitive prostate cancer (mHSPC).

In a recent study published in Nature Metabolism, researchers investigate systemic proteome adaptations to one week of fasting in humans. Study: Systemic proteome adaptions to 7-day complete caloric ...