Deep learning methods have been used to augment existing energy-based physical models in 'do novo' or from-scratch computational protein design, resulting in a 10-fold increase in success rates ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

A biochemist at the University of Washington School of Medicine has won the Nobel Prize in Chemistry for his groundbreaking work in computational protein design. When David Baker first set out decades ...

BOT or NOT? This special series explores the evolving relationship between humans and machines, examining the ways that robots, artificial intelligence and automation are impacting our work and lives.

Scientists have developed a novel approach to modifying enzymes to improve functionality. They designed a new algorithm to make multiple changes to an enzyme sequence at once as compared to the ...

On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...

Proteins are biology’s molecular machines. They’re our bodies’ construction workers—making muscle, bone, and brain; regulators—keeping systems in check; and local internet—responsible for the ...

In late 2020, AI pioneer DeepMind achieved a breakthrough 50 years in the making. By predicting the shape of proteins with atomic accuracy, its deep learning algorithm, AlphaFold, all but solved one ...

Proteins designed by artificial intelligence (AI) are being considered for use in treating everything from snakebites to cancer. A Nature Communications paper, out this week, describes how Australian ...