According to the World Health Organization, 422 million adults across the globe have diabetes. To help the growing patient population, researchers are going down to the molecular level. Here, they're ...

March 12, 2004 -- Proinsulin is a very sensitive marker of beta cell exhaustion and may therefore be useful for therapeutic decision-making in type 2 diabetes, according to the results of a study ...

A high serum proinsulin level and a low insulin-like-growth-factor-binding protein 1 (IGFBP-1) level are predictors of cardiovascular disease and diabetes in obese adults, but little evidence exists ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 10 (Mar. 6, 2007), pp. 4030-4035 (6 pages) We previously reported that diabetes in mice is associated ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 16 (Aug. 6, 2002), pp. 10299-10304 (6 pages) The neuroendocrine processing endoproteases PC2 and PC1/3 are ...

According to the World Health Organization, 422 million adults across the globe have diabetes. In fact, the number of adults with the disease continues to grow each year. To help the growing patient ...

San Diego, CA - Proinsulin, the precursor molecule of insulin, is a stronger predictor of coronary artery disease in nondiabetic men and women than insulin, a new study suggests. Dr Jee-Young Oh (Ewha ...

Scientists at Sanford Burnham Prebys Medical Discovery Institute have mapped for the first time the vast network of proteins that interact with proinsulin, the protein the body normally processes into ...

A new genetically modified form of proinsulin can reduce the autoimmune response against insulin in individuals with type 1 diabetes mellitus (T1DM) while preserving immune regulatory responses, a ...

ANN ARBOR, Mich. - According to the World Health Organization, 422 million adults across the globe have diabetes. In fact, the number of adults with the disease continues to grow each year. To help ...