Scientists have identified a promising target for treatment of a devastating autoimmune disease affecting the brain.

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment ...

Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment ...

In a study published in Cell, a research team led by Zhu Shujia from the Center for Excellence in Brain Science and Intelligence Technology of the Chinese Academy of Sciences (CAS), along with Li Yang ...

The images showed that nearly all the antibodies bind to a single domain of the receptor, providing a viable target for novel therapeutics.

The links between neurons are crucial to the brain, and brain cells can reorganize the way they are linked together in a phenomenon known as neuroplasticity. This process is ongoing during a lifetime, ...

A new study suggests a potential molecular strategy for treating fragile X syndrome, an inherited neurodevelopmental disorder that causes autism spectrum disorder and intellectual disability. This ...

Viruses. Current Pharmaceutical Design, 25(43),4579-88. 7. Wang, H.* (2022). COVID-19, Anti-NMDA Receptor Encephalitis and MicroRNA. Fronters in Immunology, 13:825103.

Three distinct snapshots obtained with cryo-electron microscopy illustrate the arrangement of two of the four symmetrical subunits that make a functional NMDA receptor. During activation, as the ...