Earlier this week, a team of researchers announced that they’d made a discovery about how we inherit mitochondrial dna from ...

Doubly uniparental inheritance (DUI) of mitochondrial DNA (mtDNA) represents a rare and intriguing deviation from the standard model of strictly maternal inheritance. In bivalves, DUI manifests as the ...

The AHA recommended whole exome or whole genome sequencing as first-line diagnostic tools for mitochondrial diseases.

Geneticists looking inside the nuclear genome for mutations that contribute to disease have long relied on a principal known as constraint modeling, which allows researchers to assess the degree of ...

The 100 or so organelles in sperm are swamped by hundreds of thousands of mitochondria embedded in each egg cell — each carrying the 37 genes in mitochondrial DNA. The contribution of only maternal ...

In most eukaryotes, the inheritance of mitochondrion and its DNA (mtDNA) is strictly maternal, despite the fact that a spermatozoon can inject up to 100 functional mitochondria into the oocyte during ...

Researchers from the Mitochondrial Medicine Program at Children's Hospital of Philadelphia (CHOP) have better characterized a spectrum of what were classically considered discrete mitochondrial DNA ...

The tiny little powerhouses of our cells: mitochondria, are unique among organelles because they carry their own tiny little genomes. This genetic material is separate from the rest of our genomic DNA ...

Recombination occurs in human mitochondrial DNA, says a team from the Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, in a “proof of concept” paper in Science this week that ...