A Dartmouth study published in Nature Communications reveals that immune cells in the brain use a surprising two-step process ...
Discovery that microglia can be effectively replaced could transform cell therapy for brain diseases
An international research team led by Professor Kiavash Movahedi from the Brussels Center for Immunology at the Vrije Universiteit Brussel has published unexpected results in the journal Immunity.
A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer's pathology in other ways. A rare but potent genetic ...
A microglia replacement approach demonstrates that brain macrophages with patient mutations from Aicardi–Goutières syndrome, a genetic, brain predominant interferonopathy, are sufficient to drive ...
Add Yahoo as a preferred source to see more of our stories on Google. Microglial receptor ADGRG1 helps immune cells eat amyloid plaques and may offer new hope for Alzheimer's treatment. (CREDIT: ...
During development, there are known sex-related differences in how microglia function. But into adulthood, there was thought to be less variation in how they behave. Microglia maintain neuronal ...
A collision happens. Someone is hurt, a head injury, a concussion. Just as the first responders arrive to help the person, inside the brain, another “crew” of responders is busy clearing debris and ...
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Aging brains struggle to recycle synaptic proteins
As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren't sure why. It is increasingly clear, though, that the loss of synapses-the flexible and adaptive relay ...
By analyzing tissue from patients with Parkinson's disease, and animal and cellular models of the disease, a research team from the Institut de Neurociències of the UAB has shown that the main immune ...
In the search for answers about Alzheimer’s disease, researchers are taking a close look at the immune system of the brain. A new study uncovers how a key immune cell, called a microglia, might be the ...
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