For many patients with diverse and seemingly unrelated symptoms, obtaining an accurate diagnosis can take years of specialist visits and inconclusive tests. Mast cell activation syndrome, a disorder ...

Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

In dogs, mast cell tumors are the most common malignant skin tumors, accounting for approximately 16–21% of all skin cancers. These tumors can appear anywhere on the body but are most frequently found ...

Please provide your email address to receive an email when new articles are posted on . Evidence of systemic mast cell activation in the PROSPECTOR study was split into three categories. A REMA score ...

Certain immune cells backstab their cellular coworkers during allergic reactions. Mast cells, the security patrols of the immune system, can trigger allergic inflammation when they run into unfamiliar ...

Eosinophils and mast cells are two types of immune cells with critical roles in responding to foreign assaults. When these cells do not function properly, several disease outcomes can develop (e.g.

According to an international multicenter study, CD2-negative mast cells are associated with significantly reduced overall survival in patients with SM. Patients with CD2-negative mast cells have ...

Canine mast cell tumours (MCTs) represent one of the most prevalent neoplasms in dogs, characterised by their markedly heterogeneous clinical behaviour. These tumours, ranging from benign lesions to ...

Editor’s note: Dr. Lee Pickett has retired, but Creators continues to distribute columns from her archive. This one is from 2022. Q: My Lab mix has a mast cell tumor. What can you tell me about this ...