Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

Researchers have identified an enzyme that controls the maturation and long-term survival of tissue-resident macrophages.

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer ...

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells. Yet despite their innate "combat" capabilities ...

Research led by Lancaster University has discovered that a class of antibiotics—fluoroquinolones—can directly alter the ...

Acute-on-chronic liver failure (ACLF) is a life-threatening syndrome characterized by systemic inflammation and immune dysregulation, in which ...

Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium urate crystals, or MSUc; CPPD disease, another inflammatory joint disease ...

To grow, cancer tumors must hijack the immune system for their needs. One of the main tricks that most tumors use is to manipulate a type of immune cell called a macrophage, causing it to protect the ...