Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and ...
A 3D liver model was engineered by a team of researchers, that accurately replicates the connection between liver cells (hepatocytes) and scarring cells (stellate cells) in the condition of fibrosis.
3D bio-printed liver model and high-content imaging for evaluating the toxicity effects of compounds
The effectiveness of non-clinical drug safety predictions is enhanced by the adoption of three-dimensional (3D) cellular models. 3D bioprinting enables the generation of complex models with spatial ...
Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and ...
Metabolic dysfunction--associated steatohepatitis or MASH (formerly known as nonalcoholic steatohepatitis) is an inflammatory, liver-scarring disease that affects 1.5% to 6.5% of all U.S. adults.
Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and ...
In a bid to gain further understanding of the etiology and pathogenesis of metabolic dysfunction–associated steatohepatitis (MASH), a team of researchers has created 3D bioprinted liver models. MASH, ...
Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...
Mitochondrial impairment is a major mechanism of action (MoA) causing drug-induced liver injury (DILI), as evidenced by drugs that have received black box warnings, 1 such as Amiodarone (used to treat ...
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