Signal transduction events following engagement of immune receptors or receptor tyrosine kinases are crucially dependent on the formation of multiprotein complexes. Adapter proteins play a key role in ...
Lymphocyte function-associated antigen 1 (LFA-1) affinity and avidity changes have been assumed to mediate adhesion to intercellular adhesion molecule-1 for T-cell conjugation to dendritic cells (DC).
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