“Trying to Be a Good Parent” As Defined By Interviews With Parents Who Made Phase I, Terminal Care, and Resuscitation Decisions for Their Children In this multisite study, 171 children with ...

The optimal chemotherapy regimen for HIV-related BL is yet to be defined. Wang et al. compared the use of cyclophosphamide, doxorubicin, vincristine, high-dose methotrexate, ifosphamide, etoposide and ...

A new study has found that high birth weight is associated with an increased risk of childhood acute lymphoblastic leukemia (ALL) but not an increased risk of acute myeloid leukemia (AML). The ...

The purpose of this study was to determine the incidence of and pharmacokinetic parameters associated with the development of transient encephalopathy following the administration of high-dose ...

Accord Healthcare, a London-based drugmaker, resumed manufacturing of two methotrexate solutions, according to a Nov. 7 update from the FDA. By March, the American Society of Health-System Pharmacists ...

Of 170 children with retinoblastoma screened at our institution for metastatic disease since the fall of 1979, 20 (12%) had extraocular tumor. Twelve of these children, including 4 with bone marrow ...

Treatment of CNS involvement entails intrathecal cytarabine and/or methotrexate until CSF cytology is clear of malignant cells. Liposomal extended-release cytarabine (DepoCyte®) has been investigated ...