Low complexity (LC) head domains 92 and 108 residues in length are, respectively, required for assembly of neurofilament light (NFL) and desmin intermediate filaments (IFs). As studied in isolation, ...

Neurofilament light (NfL) is a 68 kDa cytoskeletal intermediate filament protein highly expressed in neuronal axons. It is associated with the 125 kDa Neurofilament medium (NfM) and the 200 kDa ...

The symptoms of neurodegenerative diseases like Alzheimer’s, frontotemporal dementia, and chronic traumatic encephalopathy (CTE) are different, but they have one feature in common: the presence of ...

Glial Fibrillary Acidic Protein (GFAP) is a class-III intermediate filament that is mostly produced in astrocytic glial cells in the central nervous system. Astrocytes have important functions in ...

How did life leap from simple microbial cells to the complex, structured cells that make up animals, plants, and fungi? A new study in The EMBO Journal by researchers at the Indian Institute of ...