Understanding how a tumor evolves against the attack of the immune system is one of the greatest challenges in modern medicine. Current mathematical models are usually deterministic; that is, they ...

An international research consortium, led by scientists at VIB and UGent, has developed a new platform that could change how ...

Uncovering mechanisms regulating immune system responses is key to strengthening and redirecting them whenever necessary in cancer and infections as well as understanding autoimmune diseases. However, ...

Understanding the interaction between immune cells and cancer cells has important implications for cancer immunotherapies, including checkpoint inhibitor drugs and cell-based therapies, as well as ...

Pancreatic cancer may evade the immune system using a clever molecular trick. Researchers found that the cancer-driving ...

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how ...

Since the development of the super immunodeficient CIEA NOG mouse® in the early 2000s enabled improved humanized immune system (HIS) mice, HIS models have been widely adopted in immuno-oncology ...

Scientists at The Wistar Institute have identified a previously overlooked mediator in the body's response to ...

How does the same infection, say the flu or a cold, give some people mild symptoms and leave others suffering? Why do people develop autoimmune diseases? And will we ever be able to predict when—and ...