In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

Cells experience many different types of stress, such as starvation or stress caused by too much salt or too high a temperature. Insulin signals respond to such stress signals by sending the protein ...

AMOLF researchers discovered a mysterious interplay of insulin signals in the worm C. elegans. The insulin-driven protein DAF-16 does not only move in and out of the cell nucleus in a complex rhythm, ...