Family with sequence similarity 19 member A5 (FAM19A5) is a secretory protein highly expressed in the brain that regulates synapse dynamics through its interaction with leucine-rich repeat-containing ...

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia. How this happens remains largely ...

Clinical portfolio, informed by deep and novel synapse biology and pharmacology insights, aims to strengthen neural connections through event-driven pharmacology Lead candidate zelquistinel is ...