Inserting, removing or swapping individual atoms from the core of a molecule is a long-standing challenge in chemistry. This ...

Aliphatic alcohols are cheap, widely available, and very stable building blocks for chemical synthesis and drug discovery. Now, a team of chemists has found a way to add functional groups to them in ...

Chemists have developed new tools to modify sulfur-containing biomolecules, from simple amino acids to large protein complexes such as nucleosomes. These modifications then provide attachment points ...

Middle molecules with a molecular weight of more than 1,000 are difficult to synthesize due to multiple steps and time-consuming nature, demanding the development of a new approach that can overcome ...

The carbon-hydrogen bond -- 2/3 of all bonds in hydrocarbons -- has defied chemists' attempts to open it up and add new chemical groups. A team has now cracked the strongest of C-H bonds, those on a ...