While the large proportion of our genome that does not instruct our cells to form proteins has been harder to study than protein-coding genes, it has been shown to have vital physiological functions.

A novel bioinformatics approach for classifying proteins according to similarity of function, rather than of sequence, is described in the April 12 PNAS. Albert Y. Lau and Daniel I. Chasman of ...

The expression pattern of a single gene or multiple genes can be investigated using a technique RNA microarray. In this technique, RNA molecules are ‘spotted’ onto a solid surface. These act as probes ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

HOUSTON – (June 21, 2022) – It’s a given that certain bacteria and viruses can cause illness and disease, but the real culprits are the sequences of concern that lie within the genomes of these ...

As genes are turned into proteins, every three base pairs of DNA code for one amino acid. And because there are 64 possible strings of DNA triplets, and only 20 amino acids, some changes in DNA ...

Gain-of-function research (GOFR) refers to the serial passaging of microorganisms to increase their transmissibility, virulence, immunogenicity, and host tropism by applying selective pressure to a ...