The Fontan operation is now among the most common procedures performed to treat complex congenital cardiac defects not amenable to biventricular repair. The advent of the Norwood procedure to treat ...

In the current issue of Cardiovascular Innovations and Applications, researchers Ahmed Kheiwa, Anushree Agarwal and Anitha John from the Division of Cardiology, Department of Medicine, University of ...

Of the thousands of children born each year with congenital heart defects, a small cohort have severe malformations of their cardiac chambers leading to a single ventricle physiology. The current ...

DALLAS, July 1, 2019 -- The Fontan procedure has allowed more people born with only one ventricle -- the lower pumping chamber of the heart -- to survive into adulthood, but their unique circulatory ...

CCHMC is building a new learning network to assess long-term complications of a procedure for people born with a variety of congenital heart defects. A doctor at Cincinnati Children’s Hospital Medical ...

Mezzion Pharmaceuticals, Inc. (Mezzion), a late-stage rare disease biopharmaceutical company developing the first potential treatment for people born with single ventricle congenital heart disease (SV ...

Patients who have had surgery to create a Fontan circulation show changes in their genetic code, which may provide a new treatment opportunity to reduce premature aging. The procedure is used to treat ...

A multi-center study has identified critical risk factors that increase the likelihood of death in children with a heart defect who are awaiting or have recently undergone heart transplantation, ...

Twenty years after the publication of Fontan's landmark article, he and his colleagues [16] warned about the long-term results of the Fontan operation, expressing the fear that continuing attrition ...