One in every three FDA-approved drugs targets a single superfamily of receptors dotting the surfaces of human cells. From beta blockers to antihistamines, these essential, life-saving medications ...

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. An international team of ...

G protein-coupled receptors (GPCRs) are essential for cell signal transduction and comprise the largest drug target protein family. Upon agonist stimulation, these receptors activate multiple ...

A recent review article highlights evolving MS-based methodologies that are reshaping ligand discovery and mechanistic characterization for membrane protein drug targets. LCGC International spoke to ...

A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled receptors in living cells actually respond to activating substances. The ...

Trulance (plecanatide) is a prescription oral tablet used in adults to treat constipation due to certain conditions. This drug isn’t known to interact with other medications, but it can interact with ...

An international team involving the Institute of Chemical Research, a joint center of the University of Seville and the Spanish National Research Council, has developed a new technique that will ...

Levemir (insulin detemir) is a brand-name injection that’s prescribed for diabetes. Levemir has interactions with alcohol, some other drugs, and certain supplements. Examples include beta-blockers and ...

Eliquis (apixaban) has interactions with certain foods and supplements, including grapefruit and St. John’s wort. These interactions may make Eliquis less effective or increase the risk of side ...