PURPOSE: N-(3-Chloro-7-indolyl)-1,4-benzenedisulfonamide (E7070) is a novel sulfonamide anticancer agent currently in phase II clinical development for the treatment of solid tumors. Four phase I ...
High- and Low-Dose Interferon Alfa-2b in High-Risk Melanoma: First Analysis of Intergroup Trial E1690/S9111/C9190 PURPOSE: To characterize the pharmacokinetics of topotecan in a population model that ...
Although body weight affected pharmacokinetics, the investigators said dosing adjustments based on weight were not warranted. A new report shows the pharmacokinetic properties of Dupixent (dupilumab) ...