Uncovering a secret room that a giant virus creates inside its host amoeba

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
AZoLifeSciences on MSN

DeepCodon: A rare-codon–aware AI tool boosts protein expression in E. coli

A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...
Nature

How viral RNAs escape a host mechanism that controls translation

This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).
Science Daily

It's all in the code: Protein production efficiency can be predicted by gene sequence

Scientists explored mRNA and protein public databases to unravel hidden meanings of the genetic code. Using a metric derived from mRNA codon composition, they found out how gene sequence choice can ...

Unusual genetic code in Antarctic microbes yields rare amino acid

Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein ...
EurekAlert!

The secret room a giant virus creates inside its host amoeba

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...