“So far, nobody has been able to identify the proteins involved in mediating this widely-expressed current,” said Jorg Grandl of Duke University in Durham, North Carolina, who was not involved in this ...

A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a study led by researchers at Weill ...

Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a new study. The discovery is a ...

In a parallel development to the burgeoning field of optogenetics, scientists at the Salk Institute for Biological Studies have identified a human channel protein (hsTRPA1) and engineered it in ...

Pretein design researcher Yulai Liu holds an enlarged 3D printed model from his team's efforts to design functioning calcium channels entirely from scratch. He is standing in David Baker's lab at the ...

In a recent study posted to the bioRxiv* preprint server, researchers investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein activity in terms of calcium ...

The design of new calcium channels, built bottom-up from scratch, was reported last week in Nature. Subscribe to our newsletter for the latest sci-tech news updates. Ion channels generate electrical ...

Researchers decipher the function of an ion channel involved in cellular degradation processes and create new possibilities for Parkinson’s therapies.