Signal transduction is the fundamental process by which cells convert external cues into tailored intracellular responses. Through a cascade of molecular events—beginning at the cell membrane with the ...

Microtubules perform an active role in communication within the cell by transmitting received signals to the cell's functional units. Researchers at the Paul Scherrer Institute PSI and the Department ...

Protein tyrosine phosphatase non-receptor type 2 ( PTPN2 ) is a tyrosine phosphatase involved in T cell receptor signal ...

Edited by: Paul Smaglik D.R. Alessi, A. Cuenda, P. Cohen, D.T. Dudley, A.R. Saltiel, "PD098059 is a specific inhibitor of mitogen-activated protein kinase kinase in ...

DEATH DUEL: One TNF receptor 1 pathway activates apoptosis, another triggers gene expression-roles in seeming opposition, says David Goeddel. H. Hsu, H Shu, M. Pan, D.V. Goeddel, "TRADD-TRAF2 and ...