Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...
The field of regulated cell death has undergone a transformative shift with the discovery of novel modalities beyond apoptosis, such as ferroptosis, which ...
Gastric and esophageal cancers rank among the deadliest cancers Worldwide, due to their biological complexity, late diagnosis, and limited response to ...
Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an ...
T cells dynamically adapt to signals in the TME, transitioning between effector, exhausted, and regulatory states. Cellular interactions, metabolic stress, and physical barriers (e.g., ECM) shape ...
UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors ...
EMBL scientists discovered self-sustaining inflammatory circuits in the bone marrow stem cell microenvironment that precede blood cancers. The illustration shows cancer cells against a background of ...
Editing CAR T cells to produce inflammatory cytokines helps them enter solid tumors and promote cancer killing.
Magnetic nanoparticles engineered T cells inside living mice and guided them into solid tumors, achieving over 90% tumor ...
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