Asbestos exposure has long been considered the primary cause of mesothelioma, influencing the course of thousands of lawsuits. However, an ever-increasing body of literature supports the thesis that ...
Patients with BAP1-mutated renal cell carcinoma who were treated with Lynparza obtained responses with favorable side effect profiles. Patients with renal cell carcinoma (RCC) whose tumors had gene ...
Mesothelioma is a rare, aggressive cancer affecting the lining that surrounds organs. The most common form of the disease, pleural mesothelioma, develops in the tissue lining the lungs. The disease is ...
Researchers have identified covalently closed circular RNAs (circRNAs) from key genes involved in leukemia development and provided greater understanding of their roles in haematological malignancies.
Comparative analysis of the chromosomal origins of circulating nucleic acids in breast and prostate cancer. Background: CDKN2A and NF2 are inactivated in most MPM, but no other recurrent mutations are ...
Phase I Trial of hTERT DNA Immunotherapy Initiated in Adults with Breast, Lung, and Pancreatic Cance Patients with BAP1-mutant ccRCC have very poor prognosis and comprise 10% to 15% of ccRCC cases.
Clinical and Preclinical Activity of EGFR Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer Harboring BRAF Class 3 Mutations This was a phase II multicenter trial in which refractory solid ...
About The Study: This study found that BRCA1-associated protein (BAP1) tumor predisposition syndrome was associated with a high rate of nail abnormalities consistent with onychopapillomas (a benign ...
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