Patients with sickle cell anemia (SCA) and persistent albuminuria (PA) exhibited significantly higher levels of urinary angiotensinogen (AGT). “What we’re most excited about is that urinary ...
The renin–angiotensin–aldosterone system (RAA system) contributes to blood pressure (BP) regulation by influencing vascular tone and water–sodium reabsorption. The physiological significance of this ...
We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Zilebesiran lowered serum angiotensinogen levels and ...
SHANGHAI, April 21, 2025 /PRNewswire/ -- Rona Therapeutics, a biotechnology company pioneering innovative RNA-targeted therapies, announced that the Investigational New Drug (IND) application for ...
The drug, which interferes with RNA to reduce production of angiotensinogen, could make it possible to treat hypertension with quarterly or twice yearly subcutaneous administration. Zilebesiran, an ...
We have identified human cultured cell lines that are useful for studying angiotensinogen gene expression and its regulation in the central nervous system. A model cell system of human central nervous ...
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that it is broadening its pipeline with ALN-AGT, a subcutaneously ...
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